Can I drive from Dubai to Abu Dhabi in a rental car?

Yes, you can definitely drive a rental car from Dubai to Abu Dhabi. We do not restrict travel between emirates in the UAE.
The distance from Dubai to Abu Dhabi is 130 kilometers (80 miles) one way, making a round trip of 260 kilometers (160 miles).
Please be sure to include this mileage in your itinerary to avoid exceeding the mileage limit on your rental agreement.